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The most commonly mutated gene in cancer, p53, works to prevent tumor formation by keeping mobile elements in check that otherwise lead to genomic instability, UT Southwestern Medical Center researchers have found.

UT Southwestern Medical Center researchers developed a new imaging technique that makes X-ray images of proteins as they move in response to electric field pulses.

The Department’s Cecil H. and Ida Green Center for Reproductive Biology Sciences focuses on basic science research under the leadership of Dr. W. Lee Kraus , Professor of Obstetrics and Gynecology and Pharmacology.

Liu, a member of the Cecil H. and Ida Green Center for Reproductive Biology Sciences and a W.W. Caruth, Jr. Scholar in Biomedical Research at UTSW.

Using technology they developed, UT Southwestern Medical Center researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing.

Working with the team of co-corresponding author Gary Hon, Ph.D. , Assistant Professor of Obstetrics and Gynecology and in the Cecil H. and Ida Green Center for Reproductive Biology Sciences and the Lyda Hill Department of Bioinformatics , global gene expression analysis showed that prompting astrocytes

UT Southwestern Medical Center stem cell and developmental biologists and colleagues have developed a method to produce bovine blastoids, a crucial step in replicating embryo formation in the lab that could lead to the development of new reproductive technologies for cattle breeding.

The UT Southwestern Medical Center research focused on PARP-1, a member of the PARP enzyme family.

Researchers at UT Southwestern Medical Center have deciphered the long-sought atomic structure of PRC2, an enzyme complex that plays a key role in the development of several types of cancer, in particular blood cancer.

Beth Levine, UT Southwestern Professor of Internal Medicine and Microbiology, Director of the Center for Autophagy Research, and holder of the Charles Cameron Sprague Distinguished Chair in Biomedical Science, died Sunday after a battle with breast cancer.